WellSurvivor Breast BR-13
WellSurvivor Breast BR-13 is a multi-supplement routine specifically researched to support long-term nutritional needs and wellness goals of estrogen-positive, HER2-negative (ER+/HER2-) breast cancer survivors currently taking an aromatase inhibitor (AI) in combination with a CDK 4/6 inhibitor.
Healthcare Provider Documentation & Information:
The information below is intended for healthcare provider reference only. It summarizes supporting clinical research, ingredient rationale, and evidence-based considerations relevant to professional evaluation. This content is not intended for customer-facing use. This content is for informational and educational purposes only.
Bone Health
Vitamin D₃ (3,000 IU), Vitamin K₂ (100 µg), Magnesium (Bisglycinate 90 mg), Calcium Citrate (160 mg)
• Supports bone density & calcium balance — Endocrine guidelines emphasize sufficient calcium & vitamin D (endocrine.org+1).
• Chemotherapy-induced menopause and ovarian suppression accelerate bone loss; calcium + vitamin D prevent osteoporosis (endocrine.org).
• Vitamin K₂ improves BMD and reduces fracture risk PMC9403798.
• Magnesium intake positively correlated with BMD PubMed 34666201.
• Nutrients are non-estrogenic at these doses.
Immune Function & Wellness (Medicinal Mushrooms)
Turkey Tail, Reishi, Maitake, Lion’s Mane, Cordyceps, Chaga, Oyster (standardized extracts)
• β-Glucans activate immune receptors and NK cell activity PubMed 19515245, PMC10711352.
• Turkey Tail Phase I improved NK function DOI 10.5402/2012/251632; Reishi improved fatigue PubMed 22203880; Maitake improved immune signaling PubMed 19253021.
• Lion’s Mane improved cognition PubMed 18844328; Cordyceps immune modulation PMC9572669; Chaga autophagy DOI 10.1016/j.jep.2021.114081; Oyster ↑ T-cells PubMed 34784798.
• Safe, non-estrogenic; mild GI upset possible.
Stress Resilience
• Ashwagandha reduces stress & fatigue NIH ODS; MSK overview MSKCC.
• Apigenin supports sleep & calm Front Nutr 2024, PMC6472148; ERα modulator PMC2559959.
• Mangosteen lowers inflammation markers PubMed 26286710; MSK summary MSKCC.
• DIM promotes favorable estrogen metabolism; non-estrogenic PMC5059820.