WellSurvivor Breast BR-12
WellSurvivor Breast BR-12 is a multi-supplement routine specifically researched to support long-term nutritional needs and wellness goals of estrogen-positive, HER2-positive (ER+/HER2+) or triple positive breast cancer survivors currently taking an AI or SERDs.
Healthcare Provider Documentation & Information:
The information below is intended for healthcare provider reference only. It summarizes supporting clinical research, ingredient rationale, and evidence-based considerations relevant to professional evaluation. This content is not intended for customer-facing use. This content is for informational and educational purposes only.
Bone Health
Vitamin D₃ (2,000 IU), Vitamin K₂ (100 µg), Magnesium (Bisglycinate 90 mg), Calcium Citrate (160 mg)
• Supports bone density & calcium balance (endocrine.org+1).
• Ovarian suppression accelerates bone loss; Ca + D recommended (endocrine.org).
• Vitamin K₂ improves BMD PMC9403798; Magnesium ↑ BMD PubMed 34666201.
• Non-estrogenic nutrient profile.
Metabolic & Thyroid Function (Trace Minerals)
Zinc (8 mg), Selenium (50 µg), Iodine (50 µg), Manganese (1 mg), Chromium (100 µg), Molybdenum (45 µg)
• Zinc & Manganese support antioxidant enzymes PubMed 29186856, PubMed 22072939.
• Selenium & Iodine essential for thyroid function & immunity PubMed 26786590, PubMed 33809461.
• Iodine benefits fibrocystic breast tissue PubMed 8221402, PMC11700310.
• SIO–ASCO framework supports evidence-based, low-dose integrative use.
Antioxidant & Cellular Protection
Vitamin C (300 mg), EGCG (400 mg), Lycopene (8 mg), DIM (150 mg)
• Vitamin C collagen & immunity PMC5707683.
• EGCG reduces recurrence risk & safe with AI/fulvestrant DOI 10.3390/nu10121886, PubMed 25471334.
• Lycopene anti-proliferative PMC4317951, PMC9741066.
• DIM modulates estrogen metabolites; non-estrogenic PMC5059820.
Immune Function & Wellness (Medicinal Mushrooms)
Turkey Tail, Reishi, Maitake, Lion’s Mane, Cordyceps, Chaga, Oyster
• β-Glucans activate immune cells PubMed 19515245, PMC10711352.
• Clinical data: Turkey Tail improves NK cells DOI 10.5402/2012/251632; Reishi improves QOL PubMed 22203880; Maitake safe PubMed 19253021; Lion’s Mane ↑ cognition PubMed 18844328; Cordyceps review PMC9572669; Chaga autophagy DOI 10.1016/j.jep.2021.114081; Oyster ↑ T-cells PubMed 34784798.
• Non-estrogenic; well tolerated.
Stress Resilience & CoQ10 Support
• Ashwagandha reduces stress & fatigue NIH ODS; Apigenin calming Front Nutr 2024; anti-ERα activity PMC2559959.
• Mangosteen antioxidant support PubMed 26286710; MSK summary MSKCC.
• CoQ10 cardioprotection with trastuzumab PMC10652675; reduces anthracycline cardiotoxicity NCI PDQ; supports mitochondrial health MDPI.