WellSurvivor Breast BR-11
WellSurvivor Breast BR-11 is a multi-supplement routine specifically researched to support long-term nutritional needs and wellness goals of estrogen-positive, HER2-negative (ER+/HER2-) breast cancer survivors currently taking an AI or SERDs.
Healthcare Provider Documentation & Information:
The information below is intended for healthcare provider reference only. It summarizes supporting clinical research, ingredient rationale, and evidence-based considerations relevant to professional evaluation. This content is not intended for customer-facing use. This content is for informational and educational purposes only.
Bone Health
Vitamin D₃ (2,000 IU), Vitamin K₂ (100 µg), Magnesium (Bisglycinate 90 mg), Calcium Citrate (160 mg)
• Supports bone density & calcium balance — Endocrine guidelines emphasize sufficient calcium & vitamin D for skeletal health (endocrine.org+1).
• Chemotherapy-induced menopause & ovarian suppression accelerate bone loss; guidelines advocate calcium + vitamin D to prevent osteoporosis (endocrine.org).
• Vitamin K₂ enhances vitamin D’s effect on bone mineralization PMC9403798.
• Higher magnesium intake associated with higher BMD PubMed 34666201.
• Non-estrogenic; no evidence of ER+ activation.
Metabolic & Thyroid Function (Trace Minerals)
Zinc (8 mg), Selenium (50 µg), Iodine (50 µg), Manganese (1 mg), Chromium (100 µg), Molybdenum (45 µg)
• Zinc → SOD1 antioxidant PubMed 29186856; Manganese → SOD2 mitochondrial PubMed 22072939.
• Selenium → selenoproteins supporting redox control & thyroid PubMed 22072939.
• Molybdenum → cofactor for xanthine oxidase (NIH ODS fact sheet).
• Iodine needed for T4/T3; RDA ≈150 µg/day (NIH ODS Iodine).
• Higher selenium status linked to lower cancer risk PubMed 26786590; low SELENOP worse survival PubMed 33809461, PubMed 29043463.
• Iodine benefits fibrocystic breast disease PubMed 8221402, PMC11700310.
• Trace minerals non-estrogenic; SIO–ASCO endorsed low-risk integrative use.
Antioxidant & Cellular Protection
Vitamin C (300 mg), EGCG (Green Tea Extract) 400 mg, Lycopene (8 mg), DIM (Diindolylmethane) 150 mg
• Vitamin C supports collagen & immune health PMC5707683.
• EGCG reduces recurrence risk and safe with endocrine therapies DOI 10.3390/nu10121886, PMC7595994; no AI interactions PubMed 25471334.
• Lycopene induces apoptosis in breast cancer cells PMC4317951, PMC9741066.
• DIM supports healthy estrogen metabolism; non-estrogenic modulator PMC5059820.
Immune Function & Wellness (Medicinal Mushrooms)
Turkey Tail, Reishi, Maitake, Lion’s Mane, Cordyceps, Chaga, Oyster (standardized extracts)
• β-Glucans enhance immune surveillance PubMed 19515245, PMC10711352.
• Turkey Tail trial improved NK cell function DOI 10.5402/2012/251632; Reishi improved fatigue PubMed 22203880; Maitake improved signaling PubMed 19253021.
• Lion’s Mane enhanced cognition PubMed 18844328; Cordyceps review PMC9572669; Chaga induces autophagy DOI 10.1016/j.jep.2021.114081; Oyster ↑ T-cells PubMed 34784798.
• Non-estrogenic; safe with hormonal therapies.
Stress Resilience
• Ashwagandha reduces stress & fatigue NIH ODS; MSK monograph MSKCC.
• Apigenin supports calm/sleep Front Nutr 2024, PMC6472148; non-estrogenic ERα modulator PMC2559959.
• Mangosteen reduces CRP & oxidative stress PubMed 26286710; summarized by MSK MSKCC.